A concise total synthesis of (-)-maoecrystal Z.
نویسندگان
چکیده
The first total synthesis of (-)-maoecrystal Z is described. The key steps of the synthesis include a diastereoselective Ti(III)-mediated reductive epoxide coupling reaction and a diastereoselective Sm(II)-mediated reductive cascade cyclization reaction. These transformations enabled the preparation of (-)-maoecrystal Z in only 12 steps from (-)-γ-cyclogeraniol.
منابع مشابه
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عنوان ژورنال:
- Journal of the American Chemical Society
دوره 133 38 شماره
صفحات -
تاریخ انتشار 2011